Vampires!
Some believe the origin of vampires myths to be based on individuals suffering from a condition known as Porphyria, wherein you are unable to create hemoglobin due to a lack of porphyrins. Symptoms can include sensitivity to light (especially sunlight), anemia, change of pigmentation of the face (usually a deathly pale complexion), neurological and psychological disorders (you can go crazy), and gastrointestinal issues (cramping, nausea).
Pale crazy dude avoids the sun and tries to bite me? Sounds like a vampire to me.
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